Understanding Trifarotene (Aklief)
Medication Interactions

Trifarotene interacts with several medications. These interactions increase the risk of severity of side effects! Thus, patients need to review their current medications with their doctor. They must mention all over-the-counter drugs and supplements in addition to their prescriptions. Mentioning the skincare products they use is vital as well!
This medication interacts with eleven other ones! Two examples are isotretinoin and porfimer. Other interactions exist with aminolevulinic acid, methoxsalen, resorcinol, sulfur, methyl aminolevulinate, and verteporfin. Of course, ingredients in certain skincare products also trigger interactions with trifarotene. Such ingredients include benzoyl peroxide and salicylic acid. Thus, patients need to read the ingredient lists on every skincare product before they use them!